Plot No.367, Abhey Pur, Industrial Area Phase-1, Panchkula, Haryana 134109
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Composition : Simvastatin 20 mg tablet
Dosage Form : Tablet
Packaging Type : Blister
Packaging : 10*10
Price : ₹1/-
Simvastatin 20 mg Tablet is a lipid-lowering agent belonging to the class of HMG-CoA reductase inhibitors, commonly known as statins. It helps reduce elevated total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides while modestly increasing high-density lipoprotein cholesterol (HDL-C). Simvastatin acts by inhibiting the HMG-CoA reductase enzyme in the liver, which is crucial for cholesterol synthesis, thereby reducing circulating cholesterol levels and slowing the progression of atherosclerosis. The 20 mg strength is often used as a standard therapeutic dose for patients with moderate to severe hypercholesterolemia or those requiring additional cardiovascular risk reduction. When combined with lifestyle changes such as diet and exercise, Simvastatin 20 mg significantly lowers the risk of heart attack, stroke, and other cardiovascular events in high-risk patients.
Common side effects include headache, abdominal pain, constipation, nausea, and mild muscle aches. Rare but serious adverse effects include myopathy, rhabdomyolysis, and elevated liver enzymes, especially at higher doses or when combined with interacting drugs. The risk of muscle toxicity increases with concomitant use of potent CYP3A4 inhibitors or fibrates. Patients should report unexplained muscle pain, tenderness, or weakness immediately. Routine monitoring of liver function tests and lipid profiles is recommended during long-term use.
Simvastatin 20 mg Tablet is indicated for the treatment of primary hypercholesterolemia, mixed dyslipidemia, and hypertriglyceridemia. It is also used in the primary and secondary prevention of cardiovascular events in patients with coronary artery disease, diabetes, or multiple cardiovascular risk factors to reduce the likelihood of myocardial infarction, stroke, and the need for revascularization procedures.
Simvastatin 20 mg should be taken only under medical supervision and in conjunction with lifestyle modifications for optimal effect. It is contraindicated in pregnancy and breastfeeding as statins may harm fetal development. The medication is also contraindicated in patients with active liver disease or persistent unexplained elevations in liver transaminases. Alcohol intake should be minimized to reduce liver stress. Patients should avoid grapefruit juice while on Simvastatin, as it can increase drug levels and risk of adverse effects. Regular follow-up with lipid panels and liver function tests is essential to ensure safety and effectiveness.
Store Simvastatin 20 mg Tablet in a cool, dry place at a temperature below 30°C. Keep it protected from moisture and direct sunlight. Store in its original packaging and keep out of reach of children and pets. Do not use after the expiry date printed on the label.
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