Metofoli 600 Tablet contains Metronidazole 600 mg, a powerful nitroimidazole-class antimicrobial agent used to treat a variety of anaerobic bacterial and protozoal infections. It works by entering the cells of anaerobic organisms and disrupting their DNA synthesis, leading to cell death. This bactericidal and antiprotozoal action makes it highly effective in managing infections in low-oxygen environments such as the gastrointestinal tract, pelvis, and oral cavity. The higher strength of 600 mg is typically used in moderate to severe infections or when a higher systemic concentration is required. It is commonly employed in the treatment of pelvic infections, amoebiasis, bacterial vaginosis, dental abscesses, and as part of combination regimens in surgical prophylaxis and Helicobacter pylori eradication therapy. Metofoli 600 Tablet offers an enhanced dosing option for clinicians aiming for a more aggressive or prolonged antimicrobial effect in serious infections.
Common side effects may include nausea, a metallic or bitter taste, headache, dry mouth, and gastrointestinal discomfort. Some individuals may experience dizziness, dark urine, vomiting, or loss of appetite. Rare but serious adverse effects include peripheral neuropathy (numbness or tingling in hands/feet), seizures, and allergic skin reactions. Long-term use should be closely monitored due to the risk of hematologic toxicity and neurological effects.
Metofoli 600 Tablet is indicated for the treatment of serious anaerobic bacterial infections and protozoal infections, including amoebiasis (intestinal and hepatic), giardiasis, trichomoniasis, bacterial vaginosis, dental infections, pelvic inflammatory disease, intra-abdominal infections, and pseudomembranous colitis. It is also used in surgical prophylaxis and as adjunct therapy in combination with other antibiotics for mixed infections and H. pylori-related ulcers.
Metofoli 600 Tablet must be used under the supervision of a qualified healthcare provider. It is essential not to consume alcohol during the course of therapy and for at least 48 hours after completing the dose, as it may lead to a disulfiram-like reaction characterized by nausea, flushing, and rapid heartbeat. Caution is advised in patients with liver impairment, seizure disorders, or blood disorders. Pregnant or breastfeeding women should use this medication only if clearly needed and prescribed by a physician. Complete the full course of treatment as advised to avoid resistance or recurrence of infection. Avoid unnecessary use and follow proper dosing schedules to ensure effectiveness.
Store Metofoli 600 Tablet at a temperature below 30°C, protected from light, moisture, and excessive heat. Keep the tablets in their original packaging and out of reach of children. Do not use after the expiry date mentioned on the label.