Metoperil CT 50/12.5 Tablet is a combination medicine formulated to effectively manage high blood pressure (hypertension) and associated cardiovascular conditions. It combines Metoprolol, a selective beta-1 blocker, with Chlorthalidone, a long-acting thiazide-like diuretic, to deliver comprehensive blood pressure control by targeting both heart rate and fluid retention.
Metoprolol works primarily by blocking beta-1 adrenergic receptors in the heart. This action reduces heart rate, cardiac output, and the force of heart muscle contraction, thereby lowering blood pressure and reducing the heart’s oxygen demand. It is especially beneficial for patients with heart failure, angina (chest pain), and post-myocardial infarction (heart attack) cases.
Chlorthalidone enhances the antihypertensive effect by eliminating excess salt and water from the body through the kidneys. By reducing plasma volume, it decreases peripheral vascular resistance, which complements Metoprolol’s effects, making the combination highly effective in resistant hypertension.
This dual-action mechanism not only provides better blood pressure control but also helps reduce the risk of stroke, heart attack, and kidney problems in the long term. It is often prescribed for patients who require multi-targeted therapy and in whom single-drug treatment has been inadequate.
Metoperil CT 50/12.5 Tablet is typically taken once daily, preferably in the morning. For best results, it should be taken consistently at the same time each day, with or without food, as advised by the physician. It is important for patients to continue taking this medication even if they feel well, as hypertension often presents with no noticeable symptoms.